Esketamine under the brand name Spravato: Details on adverse reactions, price, dosage, and additional information
Spravato, also known as esketamine, is a nasal spray prescription medication used to treat certain types of depression in adult patients. The FDA has approved it for two main conditions:
- Treatment-resistant depression (TRD): Spravato is intended for adults who have not responded adequately to at least two other antidepressant treatments from different classes. It is used in combination with at least one other oral antidepressant medication.
- Major depressive disorder (MDD) with suicidal thoughts or actions: Spravato is used in this case to help quickly reduce depressive symptoms alongside other oral antidepressants.
For either condition, Spravato is only administered under medical supervision in a certified healthcare setting due to the potential side effects like sedation, dissociation, dizziness, nausea, and increased blood pressure. Patients must be monitored for at least 2 hours after dosing.
While it can be used in adults, there are age restrictions and considerations. For instance, patients must be at least 18 years old, and they should not have current or past psychosis or active substance use disorders unless they are in remission or confined in a controlled environment. Concurrent use of hallucinogens, illicit drugs, or stimulants (beyond prescribed doses) is contraindicated. Patients are also advised to abstain from alcohol or marijuana 24 hours before and after treatment.
- The mental health industry has witnessed a significant shift with the introduction of Spravato, a nasal spray medication approved for treatment-resistant depression and major depressive disorder with suicidal thoughts or actions.
- Despite its potential benefits, Spravato requires strict supervision in a certified healthcare setting due to potential side effects like sedation, dissociation, and increased blood pressure.
- In the realm of personal finance and wealth management, some investors are showing interest in the pharmaceutical industry, particularly in companies like Johnson & Johnson, which produces Spravato.
- As with any prescription medication, it's crucial for patients to understand the contraindications, such as the prohibition of concurrent use of hallucinogens, illicit drugs, stimulants, alcohol, or marijuana before and after treatment.
- It's important to note that while Spravato can be used in adults, there are age restrictions and considerations such as the minimum age requirement of 18 and the exclusion of patients with current or past psychosis or active substance use disorders unless they are in remission or confined in a controlled environment.
